Secondary structure adventures with Carl Woese

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Secondary structure adventures with Carl Woese

Not long after my arrival at UCSC as an assistant professor, I came across Carl Woese's paper "Molecular Mechanics of Translation: A Reciprocating Ratchet Mechanism." (1) In the days before the crystal structure of tRNA was known, Fuller and Hodgson (2) had proposed two alternative conformations for its anticodon loop; one was stacked on the 3' side (as later found in the crystal structure) and...

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Carl Woese

Not long after Carl Woese died, I received a message from Robin Gutell asking if I would contribute an article to this issue of RNA Biology. While my admiration for Carl's contributions to biology knows no bounds, I did not know him well personally. For that reason I advised Robin to strike my name off the list of contributors and replace it with that of someone who is better qualified than I a...

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Remembering Carl Woese

My first memory of Carl Woese was as an undergraduate at the University of Illinois. I attended a seminar course in which Carl was an instructor along with Professors Dick Davenport, Dave Stocum, and Dave Nanney. The first class was on a cold winter morning and Carl arrived late, looking hurried and wearing an impossibly large, puffy winter coat. I turned to my classmate, Doug Melton, and said ...

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Many of the authors of these short pieces (who were invited to contribute by Robin Gutell) have already written or spoken about Carl Woese since he died at the end of December 2012. My own thoughts were published in PNAS on February 26, 2013. Still saddened by Carl's death, I re-read what I wrote at that moment. The article was OK, although it was not strong enough for what Carl taught us: he d...

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Carl R. Woese (1928–2012)

The relation between science and religion is often discussed in the media — what are your views? For the large majority of scientists, religion has no direct impact on their research and this is not an issue that concerns them. But I don’t believe that we should pretend that science and religion are ‘compatible’: they are actually diametrically opposed ways of thinking and acquiring knowledge. ...

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ژورنال

عنوان ژورنال: RNA Biology

سال: 2014

ISSN: 1547-6286,1555-8584

DOI: 10.4161/rna.27970